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2008 Publications: Adkins, J.E.; Moraes, N.V.; White, N.W.; Tadlock, L.A.; Nieto, M.J.; Avery, B.A.; McCurdy, C.R., Analytical HPLC method validation for the identification of the indole alkaloid mitragynine, from extracts of Mitragyna specios., Phytochemical analysis (SUBMITTED) Agnihotri, V. K.; Elsohly, H. N.; Smillie, T. J.; Khan, I. A.; Walker, L. A., New Labdane Diterpenes from Leonurus cardiaca. Planta Med 2008. Ahmed, S. A.; Ross, S. A.; Slade, D.; Radwan, M. M.; Zulfiqar, F.; Elsohly, M. A., Cannabinoid ester constituents from high-potency Cannabis sativa. J Nat Prod 2008, 71, (4), 536-42. Bowling, J. J.; Pennaka, H. K.; Ivey, K.; Wahyuono, S.; Kelly, M.; Schinazi, R. F.; Valeriote, F. A.; Graves, D. E.; Hamann, M. T., Antiviral and anticancer optimization studies of the DNA-binding marine natural product aaptamine. Chem Biol Drug Des 2008, 71, (3), 205-15. Boyer, E. W.; Babu, K. M.; Adkins, J. E.; McCurdy, C. R.; Halpern, J. H., Self-treatment of opioid withdrawal using kratom (Mitragynia speciosa korth). Addiction 2008, 103, (6), 1048-50. Diers, J. A.; Ivey, K. D.; El-Alfy, A.; Shaikh, J.; Wang, J.; Kochanowska, A. J.; Stoker, J. F.; Hamann, M. T.; Matsumoto, R. R., Identification of antidepressant drug leads through the evaluation of marine natural products with neuropsychiatric pharmacophores. Pharmacol Biochem Behav 2008, 89, (1), 46-53. Karamyan, V. T.; Speth, R. C., Animal models of BMAA neurotoxicity: a critical review. Life Sci 2008, 82, (5-6), 233-46. Kochanowska, A. J.; Rao, K. V.; Childress, S.; El-Alfy, A.; Matsumoto, R. R.; Kelly, M.; Stewart, G. S.; Sufka, K. J.; Hamann, M. T., Secondary metabolites from three Florida sponges with antidepressant activity. J Nat Prod 2008, 71, (2), 186-9. Mallela, J.; Yang, J.; Shariat-Madar, Z., Prolylcarboxypeptidase: A cardioprotective enzyme. Int J Biochem Cell Biol 2008. Mesangeau, C.; Narayanan, S.; Green, A. M.; Shaikh, J.; Kaushal, N.; Viard, E.; Xu, Y. T.; Fishback, J. A.; Poupaert, J. H.; Matsumoto, R. R.; McCurdy, C. R., Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity. J Med Chem 2008, 51, (5), 1482-6. Peng, J.; Kudrimoti, S.; Prasanna, S.; Odde, S.; Doerksen, R. J.; Pennaka, H. K.; Choo, Y.; Rao, K. V.; Tekwani, B. L.; Shilabin, A. G.; Mayer, A. M. S.; Jacob, M. R.; Tu, L. C. T.; Gertsch, J.; Hamann, M. T., Structure Activity Relationship and Mechanism of Action Studies of Manzamine Analogues for the Control of Malaria and Neuroinflammation. Journal of the American Chemical Society (SUBMITTED) Prasanna, S.; Daga, P. R.; Xie, A.; Doerksen, R. J., Glycogen synthase kinase-3 inhibition by 3-anilino-4-phenylmaleimides: Insights from 3D-QSAR and docking. Journal of Molecular Graphics and Modelling. (UNDER REVIEW) Radwan, M. M.; Ross, S. A.; Slade, D.; Ahmed, S. A.; Zulfiqar, F.; Elsohly, M. A., Isolation and characterization of new Cannabis constituents from a high potency variety. Planta Med 2008, 74, (3), 267-72. Rumalla, C. S.; Jadhav, A. N.; Smillie, T.; Fronczek, F. R.; Khan, I. A., Alkaloids from Heimia salicifolia. Phytochemistry 2008, 69, (8), 1756-62. Thumma, S.; Majumdar, S.; Elsohly, M. A.; Gul, W.; Repka, M. A., Preformulation Studies of a Prodrug of delta 9-Tetrahydrocannabinol. AAPS PharmSci Tech. (UNDER REVIEW) Thumma, S.; Elsohly, M. A.; Zhang, S. Q.; Gul, W.; Repka, M. A., Influence of plasticizers on the stability and release of a prodrug of Delta(9)-tetrahydrocannabinol incorporated in poly (ethylene oxide) matrices. Eur J Pharm Biopharm 2008. Tumuluri, V. S.; Kemper, M. S.; Lewis, I. R.; Prodduturi, S.; Majumdar, S.; Avery, B. A.; Repka, M. A., Off-line and on-line measurements of drug-loaded hot-melt extruded films using Raman spectroscopy. Int J Pharm 2008, 357, (1-2), 77-84.
2007 Publications: Battu, S. K.; Repka, M. A.; Majumdar, S.; Madhusudan, R. Y., Formulation and evaluation of rapidly disintegrating fenoverine tablets: effect of superdisintegrants. Drug Dev Ind Pharm 2007, 33, (11), 1225-32. Bikbulatov, R. V.; Yan, F.; Roth, B. L.; Zjawiony, J. K., Convenient synthesis and in vitro pharmacological activity of 2-thioanalogs of salvinorins A and B. Bioorg Med Chem Lett 2007, 17, (8), 2229-32. Crowley, M. M.; Zhang, F.; Repka, M. A.; Thumma, S.; Upadhye, S. B.; Battu, S. K.; McGinity, J. W.; Martin, C., Pharmaceutical applications of hot-melt extrusion: part I. Drug Dev Ind Pharm 2007, 33, (9), 909-26. Giner, J. L.; Kiemle, D. J.; Kutrzeba, L.; Zjawiony, J., Unambiguous NMR spectral assignments of salvinorin A. Magn Reson Chem 2007, 45, (4), 351-4. Hamann MT, Hill R, Roggo S, Marine Natural Products. Key Advances to the Practical Application of this Resource in Drug Development, Natural Products in Drug Discovery, CHIMIA, 61, No.6, 2007 (ISSN 0009-4293) Kutrzeba, L.; Dayan, F. E.; Howell, J.; Feng, J.; Giner, J. L.; Zjawiony, J. K., Biosynthesis of salvinorin A proceeds via the deoxyxylulose phosphate pathway. Phytochemistry 2007, 68, (14), 1872-81. Repka, M. A.; Battu, S. K.; Upadhye, S. B.; Thumma, S.; Crowley, M. M.; Zhang, F.; Martin, C.; McGinity, J. W., Pharmaceutical applications of hot-melt extrusion: Part II. Drug Dev Ind Pharm 2007, 33, (10), 1043-57. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17963112 |
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The Center of Research Excellence in Natural Products Neuroscience (CORE-NPN) is funded by the National Center for Research Resources (NCRR) at the National Institutes of Health (NIH) as one of its Centers of Biomedical Research Excellence |
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