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2008 Publications:
Adkins, J.E.; Moraes, N.V.; White, N.W.; Tadlock, L.A.; Nieto, M.J.; Avery, B.A.; McCurdy, C.R., Analytical HPLC method validation for the identification of the indole alkaloid mitragynine, from extracts of Mitragyna specios., Phytochemical analysis (SUBMITTED)
Agnihotri, V. K.; Elsohly, H. N.; Smillie, T. J.; Khan, I. A.; Walker, L. A., New Labdane Diterpenes from Leonurus cardiaca. Planta Med 2008.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18666048
Ahmed, S. A.; Ross, S. A.; Slade, D.; Radwan, M. M.; Zulfiqar, F.; Elsohly, M. A., Cannabinoid ester constituents from high-potency Cannabis sativa. J Nat Prod 2008, 71, (4), 536-42.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18303850
Bowling, J. J.; Pennaka, H. K.; Ivey, K.; Wahyuono, S.; Kelly, M.; Schinazi, R. F.; Valeriote, F. A.; Graves, D. E.; Hamann, M. T., Antiviral and anticancer optimization studies of the DNA-binding marine natural product aaptamine. Chem Biol Drug Des 2008, 71, (3), 205-15.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18251774
Boyer, E. W.; Babu, K. M.; Adkins, J. E.; McCurdy, C. R.; Halpern, J. H., Self-treatment of opioid withdrawal using kratom (Mitragynia speciosa korth). Addiction 2008, 103, (6), 1048-50.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18482427
Diers, J. A.; Ivey, K. D.; El-Alfy, A.; Shaikh, J.; Wang, J.; Kochanowska, A. J.; Stoker, J. F.; Hamann, M. T.; Matsumoto, R. R., Identification of antidepressant drug leads through the evaluation of marine natural products with neuropsychiatric pharmacophores. Pharmacol Biochem Behav 2008, 89, (1), 46-53.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18037479
Karamyan, V. T.; Speth, R. C., Animal models of BMAA neurotoxicity: a critical review. Life Sci 2008, 82, (5-6), 233-46.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18191417
Kochanowska, A. J.; Rao, K. V.; Childress, S.; El-Alfy, A.; Matsumoto, R. R.; Kelly, M.; Stewart, G. S.; Sufka, K. J.; Hamann, M. T., Secondary metabolites from three Florida sponges with antidepressant activity. J Nat Prod 2008, 71, (2), 186-9.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18217716
Mallela, J.; Yang, J.; Shariat-Madar, Z., Prolylcarboxypeptidase: A cardioprotective enzyme. Int J Biochem Cell Biol 2008.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18396440
Mesangeau, C.; Narayanan, S.; Green, A. M.; Shaikh, J.; Kaushal, N.; Viard, E.; Xu, Y. T.; Fishback, J. A.; Poupaert, J. H.; Matsumoto, R. R.; McCurdy, C. R., Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity. J Med Chem 2008, 51, (5), 1482-6.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18278854
Peng, J.; Kudrimoti, S.; Prasanna, S.; Odde, S.; Doerksen, R. J.; Pennaka, H. K.; Choo, Y.; Rao, K. V.; Tekwani, B. L.; Shilabin, A. G.; Mayer, A. M. S.; Jacob, M. R.; Tu, L. C. T.; Gertsch, J.; Hamann, M. T., Structure Activity Relationship and Mechanism of Action Studies of Manzamine Analogues for the Control of Malaria and Neuroinflammation. Journal of the American Chemical Society (SUBMITTED)
Prasanna, S.; Daga, P. R.; Xie, A.; Doerksen, R. J., Glycogen synthase kinase-3 inhibition by 3-anilino-4-phenylmaleimides: Insights from 3D-QSAR and docking. Journal of Molecular Graphics and Modelling. (UNDER REVIEW)
Radwan, M. M.; Ross, S. A.; Slade, D.; Ahmed, S. A.; Zulfiqar, F.; Elsohly, M. A., Isolation and characterization of new Cannabis constituents from a high potency variety. Planta Med 2008, 74, (3), 267-72.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18283614
Rumalla, C. S.; Jadhav, A. N.; Smillie, T.; Fronczek, F. R.; Khan, I. A., Alkaloids from Heimia salicifolia. Phytochemistry 2008, 69, (8), 1756-62.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18374955
Thumma, S.; Majumdar, S.; Elsohly, M. A.; Gul, W.; Repka, M. A., Preformulation Studies of a Prodrug of delta 9-Tetrahydrocannabinol. AAPS PharmSci Tech. (UNDER REVIEW)
Thumma, S.; Elsohly, M. A.; Zhang, S. Q.; Gul, W.; Repka, M. A., Influence of plasticizers on the stability and release of a prodrug of Delta(9)-tetrahydrocannabinol incorporated in poly (ethylene oxide) matrices. Eur J Pharm Biopharm 2008.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18602993
Tumuluri, V. S.; Kemper, M. S.; Lewis, I. R.; Prodduturi, S.; Majumdar, S.; Avery, B. A.; Repka, M. A., Off-line and on-line measurements of drug-loaded hot-melt extruded films using Raman spectroscopy. Int J Pharm 2008, 357, (1-2), 77-84.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18316165
2007 Publications:
Battu, S. K.; Repka, M. A.; Majumdar, S.; Madhusudan, R. Y., Formulation and evaluation of rapidly disintegrating fenoverine tablets: effect of superdisintegrants. Drug Dev Ind Pharm 2007, 33, (11), 1225-32.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18058319
Bikbulatov, R. V.; Yan, F.; Roth, B. L.; Zjawiony, J. K., Convenient synthesis and in vitro pharmacological activity of 2-thioanalogs of salvinorins A and B. Bioorg Med Chem Lett 2007, 17, (8), 2229-32.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17303418
Crowley, M. M.; Zhang, F.; Repka, M. A.; Thumma, S.; Upadhye, S. B.; Battu, S. K.; McGinity, J. W.; Martin, C., Pharmaceutical applications of hot-melt extrusion: part I. Drug Dev Ind Pharm 2007, 33, (9), 909-26.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17891577
Giner, J. L.; Kiemle, D. J.; Kutrzeba, L.; Zjawiony, J., Unambiguous NMR spectral assignments of salvinorin A. Magn Reson Chem 2007, 45, (4), 351-4.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17351976
Hamann MT, Hill R, Roggo S, Marine Natural Products. Key Advances to the Practical Application of this Resource in Drug Development, Natural Products in Drug Discovery, CHIMIA, 61, No.6, 2007 (ISSN 0009-4293)
Kutrzeba, L.; Dayan, F. E.; Howell, J.; Feng, J.; Giner, J. L.; Zjawiony, J. K., Biosynthesis of salvinorin A proceeds via the deoxyxylulose phosphate pathway. Phytochemistry 2007, 68, (14), 1872-81.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17574635
Repka, M. A.; Battu, S. K.; Upadhye, S. B.; Thumma, S.; Crowley, M. M.; Zhang, F.; Martin, C.; McGinity, J. W., Pharmaceutical applications of hot-melt extrusion: Part II. Drug Dev Ind Pharm 2007, 33, (10), 1043-57.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17963112 |
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