PHARMACY ADMINISTRATION - PHAD

Professor Dewey D. Garner, Chair
223 Faser Hall

Professors Alidaee, Banahan, Frate, Smith, and Vitell
Associate Professors Gilbert, Juergens, Kolassa, and O'Quin
Assistant Professors Bentley, McCaffrey, and Wilkin

541, 542. PROBLEMS IN PHARMACY ADMINISTRATION. Investigation of individual problems. Prerequisite: consent of instructor. (1-4, 1-4).

543, 544. SEMINAR IN CURRENT HEALTH TOPICS. (1, 1). (Z grade).

579. PRIMARY DATA TECHNIQUES. Overview of primary research techniques used in pharmaceutical marketing research. Included questionnaire development, sampling, and data collection through various personal interview and self-administered survey methods. (3).

586. FOOD, DRUG AND COSMETIC LAW. Federal regulation of food, drugs and cosmetics, drug advertising, and products liability. (Same as LAW 689). (3).

597. MEDICAL ANTHROPOLOGY. Social factors in health and illness. Social influences on need, demand, provision, and compliance with medical care. (Same as ANTH 597). (3).

599. HEALTH CARE AND CONTEMPORARY SOCIETY. Development, current organization, and financing of the contemporary health care system in the U.S. from a comparative perspective. Specific topics include provider socialization, provider-consumer interaction, health care as an industry, and the health care system of the future. (Same as ANTH 599 and SOC 599). (3).

661. EPIDEMIOLOGY AND HEALTH DATA MANAGEMENT. Methods and techniques of health data collection with emphasis on use in health planning. (3).

672. FINANCIAL MANAGEMENT OF HEALTH CARE INSTITUTIONS. Theory and application of financial issues and techniques unique to aspects of health care institutions. (Same as FIN 636). (3).

673. SEMINAR IN HEALTH PLANNING. Application of planning techniques to regional and local health systems. Prerequisite: 661 or consent of instructor (3).

674. RESEARCH IN PHARMACY ADMINISTRATION. Investigation of individual problems. (1-3).

675. HEALTH AGENCY ADMINISTRATION. Structured, supervised experience in health care agencies. (1-3). (Z grade).

679. ADMINISTRATIVE RESIDENCY. Residency in approved health care institution or agency; written reports required. (1-6). (Z grade).

680. ADVANCED QUANTITATIVE ANALYSIS I. An examination of a number of procedures falling under the general category of analysis of variance (ANOVA), concluding with a discussion of bivariate (simple) and multiple regression. Prerequisite: a 500-level statistics course. (3).

681. ADVANCED QUANTITATIVE ANALYSIS II. An examination of the use of a number of multivariate statistical techniques, including logistic regression and discriminant analysis, conjoint analysis, cluster analysis, factor analysis, and structural equation modeling. (3).

683. ADVANCED DRUG MARKETING. Factors affecting acceptance, distribution, promotion, and economics of drug marketing. (3).

684. MARKETING HEALTH CARE SERVICES. Techniques required to identify health markets and the marketing functions necessary to meet their needs. (3).

685. HEALTH CARE ORGANIZATION AND ADMINISTRATION. Case applications of principles of health care organization. (3).

687. SECONDARY DATA TECHNIQUES. Techniques and principles useful in using secondary data to answer research questions, including data and data source evaluation, accessing and preparing secondary databases, and review of common data types and sources. (3).

688. RESEARCH METHODOLOGY AND TECHNIQUES. An introduction to the research process from project inception to its conclusion. Students will be exposed to issues surrounding the establishment of the problem statement, hypothesis generation and testing, measurement, research design, sampling theory, data collection and analysis, and ethical conduct in research. (3).

689. HEALTH SYSTEMS MANAGEMENT. Presentation of advanced management concepts supplemented with individual case studies. (3).

692. DRUG DEVELOPMENT AND MARKETING. Industrial administrative procedures in developing and marketing new drugs. (3).

693. HEALTH ECONOMICS. Economic problems of health care for the community; programs for medical and health care; financing health care. (3).

694. PHARMACEUTICAL ECONOMICS. This course will explore the multiple facets of the economics of pharmaceuticals and the pharmaceutical industry, including the role of pharmaceuticals in health care markets and the interaction of public policy and pharmaceutical markets. (3).

697. THESIS. (1-12).

797. DISSERTATION. (1-18).

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MEDICINAL CHEMISTRY - MEDC

Professor Mitchell Allen Avery, Acting Chair
417 Faser Hall

Professors Borne and Sindelar
Associate Professor Williamson
Assistant Professor Rimoldi

501. ADVANCED MEDICINAL CHEMISTRY I. Advanced study of organic medicinal agents with emphasis on names, synthesis, chemical properties, and pharmacological properties. Readings in the current literature required. Prerequisite: consent of department. (3).

502. ADVANCED MEDICINAL CHEMISTRY II. Continuation of MEDC 501. Readings in the current literature required. Prerequisite: MEDC 501. (3).

503. MEDICINAL CHEMISTRY RESEARCH METHODOLOGY. Lecture and hands-on laboratory in various methods used in medicinal chemistry research. (3).

541, 542. PROBLEMS IN MEDICINAL CHEMISTRY. Investigation of individual problems. Prerequisite: consent of instructor. (1-4, 1-4).

543, 544. SEMINAR ON CURRENT MEDICINAL CHEMISTRY TOPICS. A seminar consisting of presentations by faculty, graduate students, B.S. Pharmaceutical Science/Medicinal Chemistry track students and invited speakers. (1, 1).

609. HETEROCYCLIC COMPOUNDS. Methods of synthesis of medicinally important compounds which contain a heterocyclic ring system. (3).

610. SELECTED TOPICS IN MEDICINAL CHEMISTRY. Recent advances emphasizing mechanisms of drug action and other new concepts. (May be repeated for credit). (3).

611. DRUG ACTION AND DESIGN I. Quantitative structure-activity relationships in drug design. Introduction to the use of physical and chemical properties in drug design and elucidation of mechanism of action of medicinal agents. (3).

612. DRUG ACTION AND DESIGN II. Drugs affecting the Central Nervous System. The synthesis, chemistry, structure, and mechanism of action of drugs affecting the CNS. Prerequisite: 501 or equivalent. (3).

613. DRUG ACTION AND DESIGN III. Drugs affecting the Peripheral Nervous System. The synthesis, chemistry, structure and mechanism of action of drugs affecting the PNS. Prerequisite: 501 or equivalent. (2).

614. DRUG ACTION AND DESIGN IV. Hormones and vitamins. Structure-biological relationships, synthesis mechanisms of action and methods of molecular modification of steroid hormones, peptide hormones, vitamins and coenzymes are covered. The emphasis of this course is the use of the above knowledge in drug design and synthesis. (3).

615. DRUG ACTION AND DESIGN V. Chemotherapeutic agents. Chemistry, therapeutic, and pharmacological action of natural and synthetic agents used in combating pathogenic organisms. (3).

630. PHARMACEUTICAL PROTEIN DESIGN AND DEVELOPMENT. This course focuses on the chemical and structural characteristics of protein pharmaceuticals which make them different from conventional pharmaceutical products. (3).

643, 644. SEMINAR ON CURRENT MEDICINAL CHEMISTRY TOPICS. A seminar consisting of presentations by faculty, graduate students, B.S. Pharmaceutical Science/Medicinal Chemistry track students and invited speakers (1, 1). (Z grade).

697. THESIS. (1-12).

797. DISSERTATION. (1-18).

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PHARMACEUTICS - PHAR

Associate Professor Christy M. Wyandt, Acting Chair
109 Faser Hall

Professors Elsohly and Chambliss
Associate Professor Harland
Assistant Professors B. Avery, Repka, and Stodghill.

541, 542. PROBLEMS IN PHARMACEUTICS. Investigation of individual problems. Prerequisite: consent of instructor. (1-4, 1-4).

543, 544. SEMINAR IN CURRENT PHARMACEUTICAL TOPICS. (1, 1)

555. RADIOPHARMACEUTICALS. Introduction to radioactivity and the application of radioisotopes to pharmacy. Prerequisite: consent of instructor. (2).

558. PHARMACEUTICAL MANUFACTURING. Operation of a pharmaceutical manufacturing plant, including production, quality control, materials handling, packaging, and basic unit operation. (3-4).

630. PHARMACEUTICAL PROTEIN DESIGN AND DEVELOPMENT. This course focuses on the chemical and structural characteristics of protein pharmaceuticals which make them different from conventional pharmaceutical products. (3).

641, 642. ADVANCED PHARMACEUTICS. Advanced physical, chemical, and biopharmaceutical concepts which apply to pharmaceutical systems. (4,4).

644. SPECIAL PROBLEMS IN THE STABILITY OF PHARMACEUTICAL SYSTEMS. Investigation of individual drug stability problems using the theoretical concepts covered in 641, 642. (2-3).

645. SPECIAL PROBLEMS IN DISPERSED SYSTEMS. Investigation of individual problems encountered in dispersed pharmaceutical systems. Prerequisite: 641, 642. (2).

649. PRODUCT DEVELOPMENT. Problems involved in the development of successful formulas for medicinal products. Prerequisite: 641, 642. (3).

654. SPECIAL PROBLEMS IN BIOPHARMACEUTICS. Individual biopharmaceutical problems treating physical and chemical properties of drugs and drug systems as they relate to drug transport systems IN VIVO. Prerequisite: 641, 642. (3).

656. MATERIALS SPECIFICATIONS AND QUALITY CONTROL. Raw materials and in-process and finished product quality control procedures in the manufacture of drug products. (4).

657. RADIOISOTOPE METHODOLOGY. Application of radioisotope tracer methodology to pharmaceutical and allied science. (3).

658. RADIOISOTOPE METHODOLOGY LABORATORY. Laboratory experiments in radioisotope tracer methodology. Prerequisite: 657. (2).

660. ADVANCED PHARMACOKINETICS. A comprehensive study of the time course of drug absorption, distribution, metabolism, and excretion, and the relationship of these processes to the intensity and time course of pharmacologic effects of drugs and chemicals. Prerequisite: PHAR 642 or consent of instructor. (3).

697. THESIS. (1-12).

797. DISSERTATION. (1-18).

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PHARMACOGNOSY - PHCG

Professor Nikolaus H. Fischer, Chair
445 Faser Hall

Professors Clark, Graves, Pasco, and Zjawiony
Associate Professors Croom and Hamann
Assistant Professors Khan, Nagle, Ross, and Slattery

522. CULTIVATION AND PROCESSING OF MEDICINAL PLANTS. Cultivation, drying, and milling of plants yielding medicinal substances. (2).

541, 542. PROBLEMS IN PHARMACOGNOSY. Individual investigation of problems of current interest in pharmacognosy. (1-4, 1-4).

543, 544. SEMINAR IN TOPICS OF INTEREST ON CURRENT NATURAL PRODUCTS CHEMISTRY. (1, 1).

545, 546. INDIVIDUAL STUDY IN PHARMACOGNOSY RESEARCH. Individual readings, discussions, and presentations of research literature in natural products chemistry. (1-6, 1-6).

620. SELECTED TOPICS IN PHARMACOGNOSY. An in-depth discussion of recent advances in knowledge of plant and animal materials with biological properties of interest to pharmaceutical scientists. (May be repeated once for credit). (3).

627, 628. NATURAL PRODUCT CHEMISTRY. A comprehensive consideration of the chemistry and pharmacology of those natural product constituents important because of their biological activity. Included are the broad classes, the alkaloids, the terpenoids, the steroids, the flavanoids, and other related groups. (3, 3).

631. ANALYSIS OF NATURAL PRODUCT DRUGS. A discussion of techniques used for identification and determination of structure of substances of natural origin. Included for discussion are isolation techniques, chromatographic techniques, and micro techniques. (3).

632. ANALYSIS OF NATURAL PRODUCT DRUGS. A discussion of techniques used for identification and determination of structure of substances of natural origin. Included for discussion are physical methods and spectroscopic techniques of structure elucidation. (3).

633. ANALYSIS OF NATURAL PRODUCT DRUGS. A discussion of Fourier-transform nuclear magnet resonance techniques including 2D-NMR for the determination of structure of substances of natural origin. Prerequisite: 632. (3).

634. BIOSYNTHESIS OF PLANT CONSTITUENTS. A study of the biosynthetic pathways producing physiologically active products found in natural sources. (3).

636. FERMENTATION CHEMISTRY. Chemical aspects of the production of pharmaceutically and economically important substances by microorganisms. (3).

643, 644. SEMINAR ON CURRENT TOPICS OF INTEREST IN NATURAL PRODUCTS CHEMISTRY. (1, 1). (Z grade).

697. THESIS. (1-12).

797. DISSERTATION. (1-18).

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PHARMACOLOGY - PHCL

Professor Dennis R. Feller, Chair
303 Faser Hall

Professors Davis, Matthews, Verlangieri, Walker, Waters, and Wilson
Associate Professor Sufka
Assistant Professors Foran, Sabol, Schetz, and Willett.

541. PROBLEMS IN PHARMACOLOGY. Investigation of individual problems. Prerequisite: consent of instructor. (May be repeated for credit). (1-3).

563. INTRODUCTORY PHARMACOLOGY I. General principles of pharmacodynamics; drugs affecting central nervous system. Prerequisite: 361, 362, 373. (4).

564. INTRODUCTORY PHARMACOLOGY II. Continuation of 563. Autonomic, cardiovascular, and renal drugs; endocrinological and chemotherapeutic agents. Prerequisites: 361, 362, 373, 475, 563. (4).

567. INTRODUCTION TO RESEARCH. Orientation and basic aspects of library and laboratory research in pharmacology and toxicology. (2).

569. DRUG ABUSE EDUCATION. Pharmacological, legal, and sociopsychological aspects of drug abuse. Prerequisite: fourth-year standing, graduate standing with nonpharmacy major, or consent of instructor. (2).

641, 642. UNIFIED LABORATORY IN PHARMACOLOGY, TOXICOLOGY, AND PHYSIOLOGICAL CHEMISTRY. Fundamental experiments illustrating concepts common to the three disciplines; both in vivo and in vitro techniques will be utilized. (2, 2).

643. SEMINAR: CURRENT TOPICS IN PHARMACOLOGY AND TOXICOLOGY. (1). (Z grade).

651, 652. DIRECTED STUDIES IN PHARMACOLOGY AND TOXICOLOGY. Research tutorials requiring individual conferences, literature assignments, and laboratory experiences with departmental faculty members. (1, 1).

661, 662. ADVANCED PHYSIOLOGY. Physiology of those systems, organs, and physiological mechanisms of special significance to pharmacology, including a comparative cross-species emphasis for selected organ systems. Prerequisites: PHCL 361-364 or equivalent, or consent of instructor. (Lecture and lab). (4, 4).

663. GENERAL PHARMACOLOGY. Fundamentals of pharmacokinetic, pharmacodynamic, and receptor selectivity of various classes of biologically active agents. (Lecture). (3).

665. HUMAN NEUROBIOLOGY. Review of the neuroanatomical, neurophysiological, and neurochemical substances upon which centrally acting drugs and toxicants may act. (Lecture and lab). (4).

668. EXTERNSHIP IN PHARMACOLOGY. Credit given for participation in pharmacological screening procedures carried out in the laboratories of a pharmaceutical manufacturer. (1-8).

669. PHYSIOLOGICAL CHEMISTRY. Carbohydrate, protein, and nucleic acid structure and function, enzyme catalysis, intermediary metabolism, biochemical endocrinology, membrane structure, mechanisms of solute transport, and molecular genetics. (4).

675. GENERAL PRINCIPLES OF PHARMACOLOGY AND TOXICOLOGY I. General principles of toxicology; biotransformation of toxicants; chemical carcinogenesis, mutagenesis, teratogenisis; systemic toxicology. Prerequisite: PHCL 669 or consent of instructor. (4).

676. GENERAL PRINCIPLES OF PHARMACOLOGY AND TOXICOLOGY II. Toxicity of organic and inorganic compounds; toxins of animal and plant origin; food additives and therapeutic agents; environmental toxicology; risk assessment. Prerequisite: PHCL 675 and 669, or consent of instructor. (Lecture). (4).

677. ADVANCED TOPICS. Lectures, readings, and discussions of special areas of experimental pharmacology and allied subjects. (May be repeated for credit). (2).

679. METHODS IN TOXICOLOGY. Emphasis on the quantification of toxic responses of chemical origin. Use of toxicology in the regulatory process; principles and methods for acute and chronic toxicity; biochemical methods for reassessing organ function; reproductive toxicity testing; risk assessment of chemical hazards. (Lecture and laboratory). (4).

681. SELECTED TOPICS IN TOXICOLOGY. In-depth coverage of such topics as food additives, drug toxicity, toxicology of agricultural and industrial chemicals, clinical toxicology, toxicity of plastics; naturally occurring toxins. Prerequisite 675, 676. (May be repeated for credit). (2).

685. EXTERNSHIP IN TOXICOLOGY. Credit given for research performed in toxicology at other academic institutions or private industrial concerns. (1-8). (Z grade).

697. THESIS. (1-12).

797. DISSERTATION. (1-12).

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