Modern, well-equipped research facilities in the Thad Cochran Research Center, the Coy Waller Laboratory building, and the Maynard W. Quimby Medicinal Plant Garden include:

Repository of more than 18,000 natural product specimens, extracts, and pure compounds
NCNPR screening database including more than 30,000 samples
Specialized natural products isolation and purification laboratories
Screening laboratories for determining biological activity of natural products
Central instrumentation laboratory including nuclear magnetic resonance and mass spectrometers
Medicinal chemistry synthesis laboratories
Natural products analytical laboratories utilizing a broad spectrum of analytical techniques, including gas and liquid chromatography, densitometry, and capillary electrophoresis
Molecular modeling laboratory where sophisticated computer-based techniques reveal molecular structure properties of drugs and their targets, leading to new drug design
Production greenhouses, demonstration garden beds, shade houses, and field plots
Science library of more than 69,000 volumes in house, with electronic access to thousands more journals, databases, and books