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RECENT PUBLICATIONS
Peer-Reviewed Publications:
Crowley, M.M., Repka, M.A., Thumma, S., Upadhye, S.B., Battu, S.K., Zhang, F., Martin, C., McGinity, J. Pharmaceutical Applications of Hot-Melt Extrusion: Part I. Drug Development and Industrial Pharmacy (2007), 33(9), 909-926.
Repka, M.A., Crowley, M.M., Battu, S.K., Upadhye, S.B., Thumma, S., Zhang, F., Martin, C., McGinity, J. Pharmaceutical Applications of Hot-Melt Extrusion: Part II. Drug Development and Industrial Pharmacy (2007), 33(10), 1052-1066.
Battu, S.K., Repka, M.A., S. Majumdar, M. Rao, Formulation and Evaluation of Rapidly Disintegrating Fenoverine Tablets: Effect of Superdisintegrants, Drug Development and Industrial Pharmacy (2007), 33(11), 1225-1232.
Mididoddi, P.K. and Repka, M.A., Characterization of hot-melt extruded drug delivery systems for onychomycosis, Eur. J. Pharm. Biopharm., 66(1), 95-105, (2007).
Trey, S. M.,Wicks, D. A., Mididoddi, P. K., Repka, M. A. Delivery of Itraconazole from Extruded hydroxypropylcellulose Films. Drug Development and Industrial Pharmacy (2007), 33(7), 727-735.
Prodduturi S, Urman K. L., Otaigbe J. U., Repka M. A. Stabilization of hot-melt extrusion formulations containing solid solutions using polymer blends. AAPS PharmSciTech. (2007), 29; 8(2): Article 50.
Moore, Q. C. III, Johnson, L., Repka, M. A. and McDaniel, L. S., Immunization with PspA Incorporated into a Poly(Ethylene Oxide) Matrix Elicits Protective Immunity against Streptococcus pneumoniae, Clinical and Vaccine Immonology, (2007), 14(6), 789-791.
Munjal, M., ElSohly, M.A., and Repka, M.A., Chemical Stabilization of a Δ9-Tetrahydrocannabinol Pro-Drug in Polymeric Matrix Systems Produced by a Hot-Melt Method: Role of Microenvironment pH, AAPS PharmSciTech, 7 (3), Article 71, (2006).
M.A. Repka, M. Munjal, M.A. ElSohly and S. Ross, Temperature stability and Bioadhesive properties of D9-Tetrahydrocannabinol incorporated Hydroxypropyl cellulose Polymer Matrix Systems, Drug Devel. Ind. Pharm, 32(1), 21-32, (2006).
Munjal, M., Stodghill, S., ElSohly, M.A., and Repka, M.A., Polymeric Systems for Amorphous D9-Tetrahydrocannabinol Produced by a Hot-Melt Method. Part I: Chemical and Thermal Stability during Processing, J Pharm Sci, 95(8), 1841-1853 (2006).
Munjal, M., ElSohly, M.A., and Repka, M.A., Polymeric Systems for Amorphous D9-Tetrahydrocannabinol Produced by a Hot-Melt Method. Part II: Effect of Oxidation Mechanisms and Chemical Interactions on Stability, J Pharm Sci, 95(11), 2473-2485 (2006).
Mididoddi, P.K., Prodduturi, S. and Repka, M.A., Influence of Tartaric Acid on the Bioadhesion and Mechanical Properties of Hot-Melt Extruded Hydroxypropyl Cellulose Films for the Human Nail, Drug Dev Ind Pharm, 32(9), 1059-1066, (2006).
Majumdar S and Mitra A.K. Chemical modification and formulation approaches to elevated drug transport across cell membranes. Expert Opin Drug Deliv. 2006; 3(4):511-27.
Majumdar S, Kansara V and Mitra A.K.Vitreal pharmacokinetics of dipeptide monoester prodrugs of ganciclovir. J Ocul Pharmacol Ther. 2006, 22(4):231-41
Jo, S., Kim, J., and Kim, S. W.: Reverse thermal gelation of aliphatically modified biodegradable triblock copolymers, Macromolecular Bioscience, in press, 2006
Kim, W. J., Christensen, L. V., Jo, S., Yockman, J. W., Jeong, J. H., Kim, Y. H., Kim, S. W.: Inhibition of tumor growth with cholesteryl-oligoarginine/SiRNA targeting VEGF, Molecular Therapy, 14(3), 343-350, 2006
Haesslein, A., Ueda, H., Hacker, M., Jo, S., Ammon, D. M., Borazjani, R. N., Kunzler, J. F., Salamone, J. C., and Mikos, A. G.: Long-term release of fluocinolone acetonide using biodegradable fumarate-based polymers, J. Controlled Rel., 114, 251-260, 2006
S. N. Murthy, D.E. Wiskirchen, C.P. Bowers. Iontophoretic Drug Delivery across Human nail. (In Press 2006, J.Pharm.Sci)
Zhao Y, Murthy S.N, Hui S.W, Sen A. (2005) Induction of cytotoxic T lymphocytes by electroporation-enhanced needle-free skin immunization vaccine. Vaccine2006, 24, 1282-1290.
Murthy S.N, Vishwanath n-Octyl-b-thioglucoside enhances the transdermal permeation of ketotifen Die Pharmazie 2006, 1, 285-286.
M.A. Repka, M. Munjal, M.A. ElSohly and S. Ross, Temperature stability and Bioadhesive properties of D9-Tetrahydrocannabinol incorporated Hydroxypropyl cellulose Polymer Matrix Systems, Drug Devel. Ind. Pharm, 32(1), 21-32, (2006).
Munjal, M., Stodghill, S., ElSohly, M.A., and Repka, M.A., Polymeric Systems for Amorphous D9-Tetrahydrocannabinol Produced by a Hot-Melt Method. Part I: Chemical and Thermal Stability during Processing, J Pharm Sci, 95(8), 1841-1853 (2006).
Munjal, M., ElSohly, M.A., and Repka, M.A., Polymeric Systems for Amorphous D9-Tetrahydrocannabinol Produced by a Hot-Melt Method. Part II: Effect of Oxidation Mechanisms and Chemical Interactions on Stability, J Pharm Sci, 95(10), in press (2006).
Munjal, M., ElSohly, M.A., and Repka, M.A., Chemical Stabilization of a Δ9-Tetrahydrocannabinol Pro-Drug in Polymeric Matrix Systems Produced by a Hot-Melt Method: Role of Microenvironment pH, AAPS PharmSciTech, in press (2006).
Mididoddi, P.K., Prodduturi, S. and Repka, M.A., Influence of Tartaric Acid on the Bioadhesion and Mechanical Properties of Hot-Melt Extruded Hydroxypropyl Cellulose Films for the Human Nail, Drug Dev Ind Pharm, 32(9), in press (2006).
Venkat S. Tumuluri, Mark S. Kemper, Anjaneyulu Sheri, Seoung-Ryoung Choi, Ian R. Lewis, Mitchell A. Avery and Bonnie A. Avery The Use of Raman Spectroscopy to Characterize Hydrogenation Organic Process Research and Development, in press.
A. K. Dutta, B.A. Avery, and C. M. Wyandt, “Development and validation of a stability-indicating reversed phase HPLC method for NPC 1161C, a novel 8-aminoquinoline anti-malarial drug”, Journal of Chromatography A, 1110 (1-2) (2006) 35-45.
S. Cheboyina, J. O’Haver, and C. M. Wyandt, “A mathematical model to predict the size of the pellets formed in freeze pelletization techniques: parameters affecting pellet size and shape”, Journal of Pharmaceutical Sciences, 95 (2006) 167-180.
Majumdar S, Gunda S, Pal D and Mitra A.K. Functional Activity of a Monocarboxylate Transporter, MCT1, in the Human Retinal Pigmented Epithelium Cell Line, ARPE-19.Mol Pharm. 2005; Mar-Apr; 2 (2):109-17.
Jain R, Agarwal S, Majumdar S, Zhu X, Pal D and Mitra A.K. Bypassing P-gp Mediated Cellular Efflux of HIV-Protease Inhibitor Saquinavir by its Prodrug Modification. Int J Pharm. 2005; Oct 13; 303 (1-2):8-19.
Majumdar S, Nashed YE, Patel K, Jain R, Itahashi M, Neumann D, Hill J.M and Mitra A.K. Dipeptide Monoester Ganciclovir Prodrugs for Treating HSV-1-induced Corneal Epithelial and Stromal Keratitis: In Vitro and In Vivo Evaluations. J Ocul Pharmacol Ther. 2005; 21(6):463-74.
Murthy S.N, Vishwanath B.S, Bharath S. Bioadhesive tablets for controlled transdermal delivery of drugs. PDA journal of Pharmaceutical Science and technology.2005, 59(6), 355-359
Murthy S.N, Zhao Y, Hui S.W, Sen. Transcutaneous extraction of salicylates by electroporation for pharmacokinetic studies and therapeutic drug monitoring. J. Control. Release, 2005,105, 132-141.
S. Prodduturi, R.V. Manek, W.M. Kolling, S.P. Stodghill, M.A. Repka, Solid-State Stability and Characterization of Hot-Melt Extruded Poly(ethylene) Oxide Films, J. Pharm. Sci., 94(10), 2232-2245, (2005).
M. A. Repka, K. Gutta, S. Prodduturi, M. Munjal, S.P. Stodghill, Characterization of Cellulosic Hot-Melt Extruded Films containing Lidocaine, Eur. J. Pharm. Biopharm., 59(1), 189-95, 2005.
M. A. Repka and J. W. McGinity, Alginic Acid, Handbook of Pharmaceutical Excipients, 5th Edition, American Pharmaceutical Association, November, (2005).
V. S. Rudraraju and C. M. Wyandt, “Rheology of microcrystalline cellulose and sodiumcarboxymethyl cellulose hydrogels using a controlled stress rheometer: Part II”, International Journal of Pharmaceutics, 292 (2005) 63-73.
V. S. Rudraraju and C. M. Wyandt, “Rheological characterization of microcrystalline cellulose and sodiumcarboxymethyl cellulose hydrogels using a controlled stress rheometer: Part I”, International Journal of Pharmaceutics, 292 (2005) 53-61.
A. C. Illapakurthy, S. P. Stodghill and C. M. Wyandt, “Isothermal titration calorimetry method for determination of cyclodextrin complexation thermodynamics between artemisinin and naproxen under varying environmental conditions”, European Journal of Pharmaceutics and Biopharmaceutics. 59 (2), (2005) 325-332.
A.K. Shah, B.A. Avery and C. M. Wyandt, Content analysis and stability evaluation of selected commercial preparations of St. John’s Wort, Drug Development and Industrial Pharmacy, 31 (2005) 907-916.
Majumdar S, Macha S, Nashed Y and Mitra A.K. Expression of Peptide Transporters on Rabbit Retina: A Strategy to Improve Retinal Delivery of Ganciclovir. Letters in Drug Design and Discovery. 2004; 1(1):73-77.
Majumdar S, Duvvuri S and Mitra A.K. Membrane Transporter / Receptor Targeted Prodrug Design: Strategies for Human and Veterinary Drug Development.Adv Drug Deliv Rev. 2004; 56(10): 1437-1452.
Majumdar S, Duvvuri S and Mitra A.K. Bioreversion and Oral Bioavailability of the L-Valine Dipeptide Ester Prodrug of Acyclovir, Val-Valacyclovir, In Sprague-Dawley Rats.Clinical Research and Regulatory Affairs. 2004; 21(1): 67 – 79.
Jain R, Majumdar S, Pal D and Mitra A.K. Circumventing P-gp mediated cellular efflux of quinidine by prodrug derivatization.Mol Pharm. 2004; 1(4): 290-299.
Majumdar S, Macha S, Pal D and Mitra A.K. Mechanism of Ganciclovir Uptake by Rabbit Retina and Human Retinal Pigmented Epithelium Cell Line, ARPE-19.Curr Eye Res. 2004; Aug-Sep;29(2-3):127-36.
Duvvuri S, Majumdar S and Mitra A.K. Ocular Drug Metabolism: Role in Ocular Drug Delivery. Curr Drug Metab. 2004; Dec;5 (6):507-15.
Fisher, J. P., Jo, S., Mikos, A. G., and Reddi, A. H.: Thermoreversible hydrogel scaffolds for articular cartilage engineering. J. Biomed. Mater. Res., 71A, 268-274, 2004,
Murthy S.N, Sen. A, Zhao Y, Hui S.W, Cyclodextrin enhanced transdermal delivery of piroxicam and Carboxyfluorescein by electroporation. J. Control. Release. 2004, 99 (3) 393.
Murthy S.N, Hiremath S.R, Paranjothy K.L.K. Clinical Pharmacokinetic and Pharmacodynamic evaluation of transdermal drug delivery systems of salbutamol sulfate. Int. J. Pharm. 2004, 287, 47.
Murthy S.N, Sen. A, Hui S.W. Surfactant enhanced transdermal delivery by electroporation. J. Control. Release. 2004, 98 (2), 307
Murthy S.N, Sen. A, Zhao Y, Hui S.W. Temperature influences the post-electroporation permeability state of skin. J. Pharm. Sci, 2004 93(4), 1062.
Murthy S.N, Hiremath S.R, Paranjothy K.L.K. Preparation and Evaluation of transdermal drug delivery systems of carboxymethyl guar. Int. J. Pharm. 2004, 272 (19), 11.
M.A. Repka, M. Munjal, S. Prodduturi and P. Mididoddi, Matrix and Reservoir-Based Oral Transmucosal Systems: Tailoring Delivery Solutions. American J. Drug Delivery, 2(3), 173-192, 2004.
M. A. Repka, P. Mididoddi, S. P. Stodghill, Influence of ‘Etching’ on Human Nails for the Assessment of Treatment Modalities for Onychomycosis, Int. J. Pharm., 283(1-2), 2004.
S. Prodduturi, R.V Manek, B. Kolling, S. P. Stodghill, M.A Repka. Water vapor sorption isotherms of hot-melt extruded hydroxypropyl cellulose films: Effect on physico-mechanical properties, release characteristics and stability, J. Pharm. Sci., 93(12), 3047-3056, 2004.
S. S. Tumuluri, S. Prodduturi, M. M. Crowley, S. P. Stodghill, J. W. McGinity, B. A. Avery and M. A. Repka, The use of Near-Infrared Spectroscopy for the Quantitation of a Drug in Hot-Melt Extruded Films, Drug Devel. Ind. Pharm., 30(5), 505-511, 2004.
M. M. Crowley, A. Fredersdorf, B. Schroeder, S. Prodduturi, M. A. Repka and J. W. McGinity, The Influence of Guaifenesin and Ketoprofen on the Properties of Hot-Melt Extruded Polyethylene Oxide Films, Eur J Pharm Sci, 22, 409-418, 2004.
J. W. McGinity and M. A. Repka, Hot-Melt Extruded Films for Transmucosal and Transdermal Drug Delivery Applications, Drug Del Tech, 4(7), 72-78, 2004.
S. Cheboyina, W. G. Chambliss and C.M. Wyandt, A simple and novel freeze pelletization technique for the preparation of matrix pellets", Pharmaceutical Technology, 23(10)(2004) 98-110.
Majumdar S, Gunda S and Mitra A.K. Functional Expression of a Sodium Dependent Nucleoside Transporter on Rabbit Cornea: Role in Corneal Permeation of Acyclovir and Idoxuridine.Curr Eye Res. 2003; Mar-Apr;26(3-4):175-83.
Duvvuri S, Majumdar S and Mitra A.K. Drug delivery to retina: challenges and opportunities. Expert Opin Biol Ther. 2003; Feb;3(1):45-56.
Majumdar S, Tirucherai G.S, Pal D and Mitra A.K. Differential Expression of Nucleoside and Nucleobase Transporters on the Rabbit Corneal Epithelial Cell Line (SIRC) and Isolated Rabbit Cornea. AAPS PharmSci. 2003; 5(2):E15.
Kandhari, S. P.: Avery, M.A.; Avery, B.A. "Analytical Techniques for the Determination of Artemisinin and Its Related Analogs" Research Advances in Antimicrobial Agents and Chemotherapy, (2003) 3, 97-106.
Illapakurthy, A. C.; Sabnis, Y.A.; Avery, B. A.; Avery, M. A.; Wyandt, C.M; "Interaction of Artemisinin and its Related Compounds with Hydroxypropy-B-Cyclodextrin in Solution State: Experimental and Molecular-Modeling Studies", J. Pharm.Sci.," (2003) vol. 92, no.3.
Shin, H., Jo, S., and Mikos, A. G.: Biomimetic materials for tissue engineering, Biomaterials, 24(24), 4353-64, 2003.
Shung, K. A., Behravesh, E., Jo, S., and Mikos, A. G.: Crosslinking characteristics of and cell adhesion to an poly(propylene fumarate-co-ethylene glycol) hydrogel using a water soluble crosslinking system, Tissue Engineering, 9, 243-254, 2003
Murthy S.N, Sen. A, Zhao Y, Hui S.W. pH influences the post-pulse permeability state of the skin after electroporation- J. Control. Release. 2003, 93(18) 49 .
M. A. Repka, S. Prodduturi and S. P. Stodghill, Production and Characterization of Hot-Melt Extruded Films containing Clotrimazole. Drug Devel. Ind. Pharm. 29(7), 2003.
C. Illapakurthy, B. A. Avery, M. A. Avery, Y. A. Sabnis, and C. M. Wyandt, "Interaction of artemisinin and its related compounds with hydroxypropyl-beta-cyclodextrin in solid and solution state: Experimental and molecular modeling studies", Journal of Pharmaceutical Sciences, 92 (3) (2003) 649-655.
J.S. Williamson and C. M. Wyandt, ‘Prostate cancer: A race and age biased disease”, University of Mississippi Bureau of Pharmaceutical Sciences Continuing Education Website, November 26, 2003.
A. C. Illapakurthy, B.A. Avery, M. A. Avery, Y. A. Sabnis, and C. M. Wyandt, "Interaction of artemisinin and its related compounds with hydroxypropyl-beta-cyclodextrin in solid and solution state: Experimental and molecular modeling studies", Journal of Pharmaceutical Sciences, 92 (3) (2003) 649-655.
PRESENTATIONS
S. Upadhye, A. Singh, S. Majumdar, M.A. Repka, Effect of random methylated beta cyclodextrin on aqueous solubility, stability and permeation of the hemisuccinate ester of Delta-9-tetrahydrocannabinol, AAPS Pharm Sci, Annual AAPS National Meeting, November 2007, San Diego, CA.
S. Majumdar, S. Upadhye, S. Thumma, S. Battu, W. Gul, M. ElSohly, M. Repka, Evaluation of transbuccal delivery of tetrahydrocannabinol using hot-melt extruded transmucosal patch systems, AAPS Pharm Sci, Annual AAPS National Meeting, November 2007, San Diego, CA.
S. Thumma, S. Majumdar, M. A. ElSohly and M. A. Repka, Chemical Stability of a Pro-Drug of Delta-9-Tetrahydrocannabinol: Effect of Processing Variables and Plasticizers, AAPS Annual Meeting and Exposition, November 2007, San Diego, CA
S. Thumma, M. A. ElSohly and M. A. Repka, Bioadhesive Properties of Hot-Melt Produced Poly (Ethylene Oxide) Films for Transmucosal Delivery of a Pro-Drug of Delta-9-Tetrahydrocannabinol, AAPS Annual Meeting and Exposition, November 2007, San Diego, CA
S. Thumma, M. A. ElSohly and M. A. Repka, Transmucosal Delivery of a Pro-drug of Delta-9-Tetrahydrocannabinol: Effect of Formulation additives, AAPS Annual Meeting and Exposition, November 2007, San Diego, CA
S. Thumma, A. Singh, M. A. ElSohly and M. A. Repka, Evaluation of Non-ionic Surfactants for Transmucosal Delivery of a Pro-drug of Delta-9-Tetrahydrocannabinol, AAPS Annual Meeting and Exposition, November 2007, San Diego, CA
S. Thumma, N. N. Mohammed and M. A. Repka, Characterization of Hot-Melt Extruded Films for Transmucosal Delivery of Promethazine Hydrochloride, AAPS Annual Meeting and Exposition, November 2007, San Diego, CA
S. Thumma, N. N. Mohammed and M. A. Repka, Thermal Analysis of Promethazine Hydrochloride for Incorporation into Hot-Melt Extruded Poly (Ethylene Oxide) Matrices, AAPS Annual Meeting and Exposition, November 2007, San Diego, CA
S. Thumma, W. Deng and M. A. Repka, HPLC Method Development and Validation for Determination of Promethazine Hydrochloride in Hot-Melt Extruded Polymeric Matrices, AAPS Annual Meeting and Exposition, November 2007, San Diego, CA
M. Repka, S. Majumdar, S. Thumma, Q. Moore, L. Johnson, L. McDaniel, Hot-Melt Processed Poly (Ethylene Oxide) Matrices Incorporated with PspA Elicits Protective Immunity against Streptococcus pneumoniae, AAPS Annual Meeting and Exposition, November 2007, San Diego, CA
S. Battu, S. Boddu, S. Majumdar, M. A. Repka, Effect of Processing Conditions and Formulation Additives on Chemical Stability of a Δ9 – Tetrahydrocannabinol Prodrug in Polymeric Matrices Produced by a Hot-Melt Method, AAPS Pharm Sci, Annual AAPS National Meeting, November 2007, San Diego, CA.
N. Pavuluri, J. O' Haver and S. P. Stodghill, "Adsorption of Hydrocortisone into Pluronic F127 (Lutrol F127) Admicelles. A Surfactant-Templated Novel Drug Delivery Platform.", AAPS Pharm Sci, Vol. 8, No. S2, W4136, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
N. Pavuluri, J. O' Haver and S. P. Stodghill, "Thermodynamics of micellization of Pluronic F127, a difunctional triblock copolymer by Isothermal Titration Calorimetry.", AAPS Pharm Sci, Vol. 8, No. S2, W4303, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
Hippalgaonkar K and Majumdar S. Effect of Ophthalmic Formulation Components on Permeation of Acyclovir across Excised Rabbit Cornea. AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
Hippalgaonkar K and Majumdar S. Effect of Benzalkonium Chloride on Transcorneal Permeation of Acyclovir. South East Regional Interdisciplinary Symposium, May 2006, University of Florida.
S.N. Murthy, AAPS annual convention and Exposition 2005 Nashville, TN, “Influence of surfactants on the electroporation threshold and Transdermal delivery of drugs by electroporation”. (Symposium of Combination of medical devices). Invited Speaker.
S. Thumma, M. A. ElSohly and M. A. Repka, Preformulation Studies of a Pro-drug of Delta-9-Tetrahydrocannabinol, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
S. Thumma and M. A. Repka, Characterization of Controlled Release Matrix Tablets Containing a Water-Soluble Drug, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
S. Thumma and M. A. Repka, Screening of Commonly Used Excipients for Compatibility With Promethazine Hydrochloride, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
S. Thumma, S.Battu, and M. A. Repka, Evaluation of a Hot-Melt Extruded Mucoadhesive Matrix Formulation Containing a Water-Soluble Drug: Effect of Screw Speed, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
S. Battu, M. Yamsani, M.A. Repka, "Formulation of Rapidly Disintegrating Fenoverine Tablet - Effect of Superdisintegrants". South East Regional Interdisciplinary Symposium, May 2006, University of Florida.
S. Battu, M. Yamsani, M. Soumyajit, M. A. Repka, Formulation and Evaluation of Rapidly Disintegrating Fenoverine Tablets, AAPS Pharm Sci, Annual AAPS National Meeting October/November 2006, San Antonio, TX.
S. Battu, M. A. Repka, M. Yamsani, In Vivo Evaluation of Disintegration Time and Taste of Fenoverine Rapidly Disintegrating Tablets, AAPS Pharm Sci, Annual AAPS National Meeting October/November 2006, San Antonio, TX.
M. Munjal, S. Upadhye, M. Elsohly, M. A. Repka, Effect of Formulation and Physiological Variables on Permeation of ?9 – Tetrahydrocannabinol, AAPS Pharm Sci, Annual AAPS National Meeting October/November 2006, San Antonio, TX.
M. Munjal, S. Battu, M. Elsohly, M. A. Repka, Mechanistic Understanding of Dissolution Properties of Physical Mixtures and Hot – Melt Polyethylene Oxide Matrices Containing ?9 – Tetrahydrocannabinol, AAPS Pharm Sci, Annual AAPS National Meeting October/November 2006, San Antonio, TX.
M. Munjal, S. Thumma, M. Elsohly, M. A. Repka, Factors Affecting Oxidation of ?9 – Tetrahydrocannabinol in Hot – Melt Polymeric Films, AAPS Pharm Sci, Annual AAPS National Meeting October/November 2006, San Antonio, TX.
M. Munjal, S. Majumdar, M. Elsohly, M. A. Repka, Reduced Oxidation of ?9 – Tetrahydrocannabinol in Hot – Melt Polyethylene Oxide – Vitamin E Succinate Films Utilizing Anti – Oxidants, AAPS Pharm Sci, Annual AAPS National Meeting October/November 2006, San Antonio, TX.
S. Upadhye, M.A. Repka, S. R. Kulkarni, Formulation and characterization of chlorophyllin gels for wound healing potential, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
S. Upadhye, M.A. Repka, S. R. Kulkarni, Extraction, isolation and standardization of chlorophyll ‘a’ from spinach leaf, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
P. P. Budukh, J.S. Williamson and C.M. Wyandt, “Thermodynamics of binding of sulfonamide related compounds to bovine carbonic anhydrase II: An isothermal titration calorimetric study”, accepted for presentation at the American Association of Pharmaceutical Scientists Meeting, San Antonio TX, 10/06.
P. P. Budukh, J.S. Williamson and C.M. Wyandt, “Assessing functional stability of enzymes in solution using enzyme-inhibitor interactions: application of isothermal titration calorimetry”, accepted for presentation at the American Association of Pharmaceutical Scientists Meeting, San Antonio TX, 10/06.
N. Pavuluri, J. O' Haver and S. P. Stodghill, "Adsolubilization of Hydrocortisone in Triton X-100 Admicelles.", AAPS Pharm Sci, Vol. 7, No. S2, W5157, Annual AAPS National Meeting, November 2005, Nashville, TN.
M. A. Repka, S. Prodduturi, M.R. Jacob, S.I. Khan and S.P. Stodghill, Formulation and Characterization of Hot-Melt Extruded Antifungal Denture Adhesive Films, J Dent Res 84(Spec Iss A):0724, 2005
P. Mididoddi, T. Durig, R. Grasso, M.A. Repka, Influence of Hydroxypropyl cellulose molecular weight on the release properties of Polymeric Films containing a Model Antifungal Drug, AAPS Pharm Sci, Volume 7, M1219, Annual AAPS National Meeting, November 2005, Nashville, TN.
P. Mididoddi, S. Thumma, T. Durig, R. Grasso, M.A. Repka, Miscibility Predictions of Polymers and Model Drugs by Solubility Parameter Calculation and Thermal Analysis, AAPS Pharm Sci, Volume 7, W5144, Annual AAPS National Meeting, November 2005, Nashville, TN.
M. Munjal, P. B. Lindgren, H. C. Fyke, M. A. ElSohly, M. A. Repka, Oral Transmucosal Delivery of Tetrahydrocannabinol and Pro-drugs via Hot-melt Polymeric Matrices: In-vivo Studies in Rabbits, AAPS Pharm Sci, Volume 7, M1176, Annual AAPS National Meeting, November 2005, Nashville, TN.
M. Munjal, S. Thumma, M. A. Repka, Preformulation Studies of Tetrahydrocannabinol and its Pro-drugs for Preparation of Stable Hot-Melt Polymeric Systems, AAPS Pharm Sci, Volume 7, W5150, Annual AAPS National Meeting, November 2005, Nashville, TN.
S. Thumma, M.A. Repka, Formulation of a delta-9-tetrahydrocannabinol pro-drug utilizing poly(ethylene oxide) matrices, AAPS Pharm Sci, Volume 7, W5174, Annual AAPS National Meeting, November 2005, Nashville, TN.
Jacob, Melissa; Khan, Shabana; Prodduturi, Suneela; Repka, Michael; Stodghill, Steven, Increasing the Effectiveness of Antifungal Drugs Using Poly(Ethylene Oxide) and/or Hydroxypropyl Cellulose in the Formulation, AAPS Pharm Sci, Volume 7, R6117, Annual AAPS National Meeting, November 2005, Nashville, TN.
P. Mididoddi, S. Wei, J. O'Haver, M.A. Repka, Influence of ‘Etchant’ Exposure Concentration and Time on the Morphology of the Human Nail, AAPS Pharm Sci, Volume 7, W5120, Annual AAPS National Meeting, November 2005, Nashville, TN.
M. Munjal, S. P. Stodghill, M. A. Repka, Stability Indicating HPLC Method and Screening of Hyoscyamine Sulfate for Hot-Melt Extrusion, AAPS Pharm Sci, Volume 7, W5149, Annual AAPS National Meeting, November 2005, Nashville, TN.
Mark S. Kemper, Ian R. Lewis, Sri Venkata S. Tumuluri, Mitchel A. Avery, Anjaneyulu Sheri, Seoung-R. Choi and Bonnie A. Avery “The Use of Raman Spectroscopy to Characterize Hydrogenation” International Forum on Process Analytical Chemistry (IFPAC) 2005 (Arlington, VA).
A. Shah, J.S. Williamson and C. M. Wyandt, “Factors that influence the solubilization of a very hydrophobic tubulin-binding agent”, American Association of Pharmaceutical Scientists Meeting, Nashville TN, 11/05.
S. Cheboyina and C. M. Wyandt, “Development and evaluation of sustained release wax pellets by the freeze pelletization technique”, American Association of Pharmaceutical Scientists Meeting, Nashville TN, 11/05.
S. Cheboyina, J. O’Haver and C. M. Wyandt, “A mathematical model to predict the size of the pellets formed in freeze pelletization techniques: parameters affecting pellet size and shape”, American Association of Pharmaceutical Scientists Meeting, Nashville TN, 11/05.
P. P. Budukh, J. S. Williamson and C.M. Wyandt, “Correlating functional stability of enzymes with enzyme-inhibitor interactions studied by isothermal titration calorimetry”, American Association of Pharmaceutical Scientists Meeting, Nashville TN, 11/05.
A. K. Dutta, J. S.Williamson and C.M. Wyandt, “The use of isothermal titration calorimetry to study the complexation of 8-aminorquinoline with hydroxypropyl beta-cyclodextrin and sulfobutylether cyclodextrin”, American Association of Pharmaceutical Scientists Meeting, Nashville TN, 11/05.
A.K. Dutta, J. S.Williamson and C. M. Wyandt, “Solution-state characterization of inclusion complexes of 8-aminoquinoline with sulfobutylether beta-cyclodextrin using phase solubility analysis and isothermal titration calorimetry”, American Association of Pharmaceutical Scientists Meeting, Nashville TN, 11/05.
A.K. Dutta, J.S. Williamson and C.M. Wyandt, “The use of isothermal titration calorimetry to study the complexation of 8-aminorquinoline with hydroxypropyl beta-cyclodextrin and sulfobutylether cyclodextrin”, Current Tends in Microcalorimetry Conference, Boston, MA, 7/05.
P.P Budukh, J.S. Williamson, and C. M. Wyandt, “Estimation of enzyme activity by enzyme-inhibitor interactions using isothermal titration calorimetry”, Current Tends in Microcalorimetry Conference, Boston, MA, 7/05.
Majumdar S, Pal D and Mitra A.K. Peptide Transporter Targeted Drug Delivery: Evaluation of Di-peptide Monoester Prodrugs of Ganciclovir. American Association of Pharmaceutical Scientists Annual Meeting, November 2004, Baltimore, MD.
Majumdar S, Nashed Y.E., Mitra A.K., Hill J.M., Itahashi M., Trahan S.G., Anand B.S., and Thompson H.W. Antiviral Efficacy of Dipeptide Ganciclovir and Acyclovir Prodrugs, Val-Val-Ganciclovir (VVGCV) and Gly -Val-Acyclovir (GVACV), Against HSV-1 Corneal Epithelial Keratitis in the Rabbit. Association for Research in Vision and Ophthalmology Annual Meeting, Ft. Lauderdale, 2004.
Jain R, Majumdar S, Nasheed Y.E. and Mitra A.K. In Vitro Activity and Transport of Dipeptide Monoester Prodrugs of Ganciclovir across Isolated Rabbit Cornea. Association for Research in Vision and Ophthalmology Annual Meeting, Ft. Lauderdale, 2004.
M. S. Kemper, I. R. Lewis, S. Prodduturi, V. S. Tumuluri, M. M. Crowley, B. A. Avery, and M. A. Repka. "The use of off-line and on-line Raman spectroscopy to quantify ketoprofen and clotrimazole in hot-melt extruded film formulations" The Pittsburgh Conference, Chicago, IL - March 2004".
P.K. Mididoddi, S.P. Stodghill, M.A. Repka. Physico-chemical Properties and Stability Studies of ketoconazole-incorporated Hot-melt Extruded Films for Onychomycosis, The AAPS Journal Vol. 6, No. 4, Abstract W5230 (2004)
S. Prodduturi, R. V. Manek, W. M. Kolling, S. P. Stodghill, M. A. Repka, Hot-melt Extruded Polymeric Films for Transmucosal Drug Delivery: Tailoring Properties Using Polymer Blends, The AAPS Journal Vol. 6, No. 4, Abstract T3296 (2004)
S. Prodduturi, S. Thumma, M. R. Jacob, S. P. Stodghill, M. A. Repka, Hot-melt Extrusion of Thermally Stable and Unstable Model Antifungal Drugs: Process Variables and Formulation Evaluation, The AAPS Journal Vol. 6, No. 4, Abstract T2153 (2004)
P.K Mididoddi, S. Prodduturi and M. A. Repka, Mechanical Properties of Hot-melt Extruded Hydroxypropylcellulose Films Containing a Model Antifungal Drug, The AAPS Journal Vol. 6, No. 4, Abstract R6161 (2004)
S. Prodduturi, K. L. Urman, J. Otaigbe, S. P. Stodghill, M. A. Repka, Dynamic Mechanical Analysis: Determining the Mechanical Properties and Glass Transition Temperatures of Hot-melt Extruded Hydroxypropyl Cellulose Films, The AAPS Journal Vol. 6, No. 4, Abstract R6179 (2004)
P. K. Mididoddi and M. A. Repka, Influence of 'Etching' and Instrument Variables on the Bioadhesion of Hot-melt Extruded Drug Delivery Systems for the Human Nail, The AAPS Journal Vol. 6, No. 4, Abstract T3209 (2004)
S. Prodduturi, A. K. Shah, S. Thumma, B. A. Avery, M. A. Repka, Stability-indicating HPLC Method Development and Validation for Determination of Clotrimazole in Hot-melt Extruded Polymeric Matrices, The AAPS Journal Vol. 6, No. 4, Abstract T2034 (2004)
M. Munjal, S.P. Stodghill, M.A. Repka, Formulating Solid Dispersions of Amorphous Poorly Water-Soluble Tetrahydrocannabinol, The AAPS Journal Vol. 6, No. 4, Abstract M1257 (2004)
M. Munjal, M.A. Repka, Improving Stability of Amorphous Tetrahydrocannabinol in Polymeric Systems, The AAPS Journal Vol. 6, No. 4, Abstract R6086 (2004)
M. Munjal, M.A. Repka, Chemical Stabilization of an Unstable Tetrahydrocannabinol Pro-Drug in Polymeric Matrix Systems Produced by a Hot-Melt Method, The AAPS Journal Vol. 6, No. 4, Abstract R6085 (2004)
M. A. Repka, S. Prodduturi, S. P. Stodghill. Evaluation of Hot-Melt Extruded Films Containing Antifungals for the Treatment of Oral Candidiasis, IADR/AADR International Annual Meeting, Abstract 1163, Journal of Dental Research, Vol. 83, Issue A, March (2004)
M. S. Kemper, I. R. Lewis, S. Prodduturi, V. S. Tumuluri, M. M. Crowley, M. A. Repka and B. A. Avery , “The use of off-line and on-line Raman spectroscopy to quantify ketoprofen and clotrimazole in hot-melt extruded film formulations” The Pittsburgh Conference, Chicago IL March 2004.
Mark S. Kemper, Ian R. Lewis1, Sri Venkata S. Tumuluri, Mitchell A. Avery, Anjaneyulu Sheri, Seoung-R. Choi and Bonnie Avery “The Use of Raman Spectroscopy to Characterize Hydrogenation” Reactions Federation of Analytical Chemistry and Spectroscopy Societies (FACCS) 2004 (Portland, OR)
M. S. Kemper, I. R. Lewis, S. Prodduturi, V. S. Tumuluri, M. M. Crowley, M.A. Repka, and B. A. Avery, “The use of off-line and on-line Raman spectroscopy to quantify ketoprofen and clotrimazole in hot-melt extruded film formulations” Eastern Analytical Symposium (EAS) 2004 (Somerset, NJ)
Mark S. Kemper, Ian R. Lewis, Sri Venkata S. Tumuluri2 Mitchell A. Avery, Anjaneyulu Sheri, Seoung-R. Choi and Bonnie A. Avery “The Use of Raman Spectroscopy to Characterize Hydrogenation” Eastern Analytical Symposium (EAS) 2004 (Somerset, NJ)
Mark S. Kemper, Ian R. Lewis, Sri Venkata S. Tumuluri, Mitchel A. Avery, Anjaneyulu Sheri, Seoung-R. Choi and Bonnie A. Avery “The Use of Raman Spectroscopy to Characterize Hydrogenation”, AAPS 2004 (Baltimore, MD)
M. S. Kemper, I. R. Lewis, S. Prodduturi, V. S. Tumuluri, M. M. Crowley, M.A. Repka, and B.A. Avery, “The use of off-line and on-line Raman spectroscopy to quantify ketoprofen and clotrimazole in hot-melt extruded film formulations”, International Forum on Process Analytical Chemistry (IFPAC) 2004 (Arlington, VA).
A.K. Dutta, and C. M. Wyandt, “Binary phase complexation of a weak base with hydroxylpropyl beta-cyclodextrin in aqueous and buffer medium”, American Association of Pharmaceutical Scientists Meeting, Baltimore MD, 11/04.
A.K. Shah, J. S. Williamson, S. P. Stodghill and C.M. Wyandt, “Characterization of novel tubulin binding agent and its comparison with taxol”, American Association of Pharmaceutical Scientists Meeting, Baltimore MD, 11/04.
D. Pabbisetty, L. Li, P. Carvalho, M. Avery and B. A. Avery, “Quantitative determination of artemisinin in rat serum using UPLC/MS/MS”, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
V. Tumuluri，Ｓ. Ｃheboyina, D. Pabbisetty, B. Avery，"Near Infrared Spectroscopic method for the Determination of a Model Drug in Pellet Formulations", AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
D.Pabbisetty, L.Li, P.Carvalho, M.Avery and B.A.Avery, “Quantitative determination of CoQ10 in rat serum using UPLC/MS/MS”, AAPS Pharm Sci, Annual AAPS National Meeting, November 2007, San Diego, CA.
D.Pabbisetty, L.Li, P.Carvalho, M.Gundluru, M.Avery and B.A.Avery, “Determination of pKa, protein binding and plasma stability of ARB189, a novel antimalarial drug using UPLC/MS/MS”, Annual AAPS National Meeting, November 2007, San Diego, CA.
L.Li, D.Pabbisetty, M.Avery and B.A.Avery, “Urinary excretion study of Coenzyme Q10 in rat by ultra performance liquid chromatography-mass spectrometry”, AAPS Pharm Sci, Annual AAPS National Meeting, November 2007, San Diego, CA.
L.Li, D.Pabbisetty, M.Gundluru, M.Avery and B.A.Avery, “Determination of ARB189 a novel antimalarial drug in rat serum by UPLC/MS/MS and its application in pharmacokinetics”, AAPS Pharm Sci, Annual AAPS National Meeting, November 2007, San Diego, CA.
D.Pabbisetty, L.Li, P.Carvalho, M.Avery and B.A.Avery, “Analysis of CoQ10 in rat serum after oral administration using UPLC/MS/MS”, AAPS Pharm Sci-Pharm Forum, May 2007, University of Tennessee, Memphis, TN.
D.Pabbisetty, L.Li, P.Carvalho, M.Avery and B.A.Avery, “Quantitative determination of artemisinin in rat serum using UPLC/MS/MS”, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
V.Tumuluri, S.Cheboyina, D.Pabbisetty and B.A.Avery, “Near infrared spectroscopic method for the determination of a model drug in pellet formulations”, AAPS Pharm Sci, Annual AAPS National Meeting, October/November 2006, San Antonio, TX.
S. Thumma, S. Majumdar, M. A. ElSohly and M. A. Repka, Chemical Stability of a Pro-Drug of Delta-9-Tetrahydrocannabinol: Effect of Processing Variables and Plasticizers, The AAPS Journal Supplement, Volume 9, Issue S2, M1271, Annual AAPS National Meeting, November 2007, San Diego.
S. Thumma, M. A. ElSohly and M. A. Repka, Bioadhesive Properties of Hot-Melt Produced Poly (Ethylene Oxide) Films for Transmucosal Delivery of a Pro-Drug of Delta-9-Tetrahydrocannabinol, The AAPS Journal Supplement, Volume 9, Issue S2, M1272, Annual AAPS National Meeting, November 2007, San Diego.
S. Thumma, M. A. ElSohly and M. A. Repka, Transmucosal Delivery of a Pro-drug of Delta-9-Tetrahydrocannabinol: Effect of Formulation additives, The AAPS Journal Supplement, Volume 9, Issue S2, M1263, Annual AAPS National Meeting, November 2007, San Diego.
S. Thumma, A. Singh, M. A. ElSohly and M. A. Repka, Evaluation of Non-ionic Surfactants for Transmucosal Delivery of a Pro-drug of Delta-9-Tetrahydrocannabinol, The AAPS Journal Supplement, Volume 9, Issue S2, M1273, Annual AAPS National Meeting, November 2007, San Diego.
S. Thumma, N. N. Mohammed and M. A. Repka, Characterization of Hot-Melt Extruded Films for Transmucosal Delivery of Promethazine Hydrochloride, The AAPS Journal Supplement, Volume 9, Issue S2, M1270, Annual AAPS National Meeting, November 2007, San Diego.
S. Thumma, N. N. Mohammed and M. A. Repka, Thermal Analysis of Promethazine Hydrochloride for Incorporation into Hot-Melt Extruded Poly (Ethylene Oxide) Matrices, The AAPS Journal Supplement, Volume 9, Issue S2, M1274, Annual AAPS National Meeting, November 2007, San Diego.
S. Thumma, W. Deng and M. A. Repka, HPLC Method Development and Validation for Determination of Promethazine Hydrochloride in Hot-Melt Extruded Polymeric Matrices, The AAPS Journal Supplement, Volume 9, Issue S2, M1260, Annual AAPS National Meeting, November 2007, San Diego.
S. Majumdar, S. Upadhye, S. Thumma, S. Battu, W. Gul, M. A. ElSohly and M. A. Repka, Evaluation of transbuccal delivery of tetrahydrocannabinol using hot-melt extruded transmucosal patch systems, The AAPS Journal Supplement, Volume 9, Issue S2, M1247, Annual AAPS National Meeting, November 2007, San Diego.
M. Repka, S. Majumdar, S. Thumma, Q. Moore, L. Johnson and L. McDaniel, Hot-Melt Processed Poly (Ethylene Oxide) Matrices Incorporated with PspA Elicits Protective Immunity against Streptococcus pneumoniae, The AAPS Journal Supplement, Volume 9, Issue S2, T3361, Annual AAPS National Meeting, November 2007, San Diego.
S. Upadhye, A. Singh, S. Majumdar and M. A. Repka, Effect of random methylated beta cyclodextrin on aqueous solubility, stability and permeation of the hemisuccinate ester of Delta-9-tetrahydrocannabinol, The AAPS Journal Supplement, Volume 9, Issue S2, M1293, Annual AAPS National Meeting, November 2007, San Diego.
S. Battu, S. Boddu, S. Majumdar and M. A. Repka, Effect of Processing Conditions and Formulation Additives on Chemical Stability of a Δ9–Tetrahydrocannabinol Prodrug in Polymeric Matrices Produced by a Hot-Melt Method, The AAPS Journal Supplement, Volume 9, Issue S2, M1314, Annual AAPS National Meeting, November 2007, San Diego.
S. Majumdar, K. Hippalgaonkar, R. Srirangam and M. A. Repka, Effect of topical instillation of chitosan on intraocular pressure and corneal permeability in the rabbit model, The AAPS Journal Supplement, Volume 9, Issue S2, T3198, Annual AAPS National Meeting, November 2007, San Diego.
K. Hippalgaonkar, R. Srirangam, S. Majumdar, W. Gul, M. A. ElSohly and M. A. Repka, Physicochemical properties of delta-8 tetrahydrocannabinol, The AAPS Journal Supplement, Volume 9, Issue S2, W4308, Annual AAPS National Meeting, November 2007, San Diego.
GRANTS AND CONTRACTS
“Electroporation and Transcutaneous Extraction of Drugs”, Principal Investigator; S.N. Murthy. Grant # 1R15AR053097-01, Agency: NIAMS/NIH, Direct Costs: $100,000
“Oral Absorption of Hesperidin”, Principal Investigator: S. Majumdar. Agency: Industry, Research Contract: $ 2,500.00
“Berberine Project”, Principal Investigator: S. Majumdar. Agency: Industry, Research Contract: $ 12,500.00
“Center of Research Excellence in Natural Products Neuroscience (CORE-NPN)” NIH, NCRR, Principal Investigator: Rae Matsumoto, Individual Project Funded: “Characterization, Formulation and Evaluation of THC Pro-drugs for Oral Transmucosal Delivery”, PI of Individual Project: M.A. Repka, Co-PI of Individual Project, S. Majumdar, Total Costs: $1,117,000
"Antifungal Denture Adhesive Film for Oral Candidiasis" - Principal Investigator - Thomas G. Gerding; - Principal Investigator at UM - M. A. Repka; CoPI - Steven P. Stodghill; Agency - Agency - NIDCR/NIH - Grant #R43 DE 15455-01 - $99,923.
"Assessing Tetrahydrocannabinol (THC) Pro-drugs in Transmucosal Patch Delivery Formulations for the Treatment of Neuropathological Conditions". Grant #P20 RR 17701; PI of Center - G. Ordway; Principal Investigator - M. A. Repka; Agency - Center for Psychiatric Neuroscience at UMMC/COBRE/NIH; $50,000.
"Transmucosal Intra-Oral Delivery System for THC"; Principal Investigator - M. A. ElSohly; Principal Investigator at UM - M. A. Repka; Grant #1 R41 GM067304-01; Agency - GM/NIH; $99,981.
"Entrepreneurship at the Interface of Polymer Science and Medicinal Chemistry". Principal Investigator - L. J. Mathias; Pharmaceutics Investigator at UM - M. A. Repka; Agency - NSF; Award #0333136; $3,609,280.
"Properties of Hot-Melt Extruded Films Containing Klucel Polymers"; Principal Investigator - M. A. Repka; Agency - Aqualon Division, Hercules, Inc.; Research and Supplies - $9,280.
"Transmucosal Matrix Patch System for Delivery of an Antihistamine", Principal Investigator: M.A. Repka, Co-Pi: Steven P. Stodghill. Agency: Undisclosed Industry; Research Contract - $55,980.00
PATENTS/LICENSE AGREEMENTS
A Licensing Agreement between The University of Mississippi and a medium pharma was signed in May 2003. The following patents are the subject of the license; M. A Repka and T. G. Gerding, "Bioadhesive Polyethylene Glycol Ointment for Medicaments," U. S. Patent, No. 5,714,165, (1998).---M. A. Repka and T. G. Gerding, Polyethylene Glycol Ointment for Aphthous Ulcers, U. S. Patent No. 5,112,620, (1992).
A Licensing Agreement between The University of Mississippi and an undisclosed pharma was signed in February 2005, in conjunction with a Research Contract, for development of an intra-oral drug delivery system (Re: U.S. Patent # 6,375,963).
The following U. S. Patent was issued in April, 2002:---M. A. Repka, S. L. Repka and J. W. McGinity, "Bioadhesive Hot-Melt Extruded Film for Topical and Mucosal Adhesion Applications and drug Delivery and Process for Preparation Thereof. U.S. Patent, No. 6,375,963, (2002).
Jo, S. and Piao, A. Z., Biodegradable diblock copolymers having reverse thermal gelation properties and their use in pharmaceutical delivery, enhancing drug delivery and solubility., U.S. Pat. Appl. Publ. (US 20060034889), 2006.
Ammon, D. M., Salamone, J. C., Ueda, H., Jo, S., and Mikos, A. G., Injectable Biodegradable Drug Delivery System, U.S. Pat. Appl. Publ. (US 20060018949), 2006.
Jo, S. and Mikos, A. G., Biocompatible macromers, U.S. Patent No. 6,884,778, April 26, 2005
Jo, S. and Mikos, A. G., Functionalized poly(propylene fumarate) and poly(propylene fumarate-co-ethylene glycol), U.S. Patent No. 6,306,821, October 23, 2001
Chen, J., Jo, S., and Park, K., Hydrophilic, hydrophobic, and thermoreversible saccharide gels and foams, and methods for producing same, U.S. Patent No. 6,018,033, January 25, 2000
McPherson, T., Jo, S., and Park, K., Grafting of biocompatible hydrophilic polymers onto inorganic and metal surfaces., U.S. Patent No. 6,013,855, January 11, 2000, PCT/W.I.P.O. Application on August 6, 1997.
M.A. Repka and M.A. ElSohly, Alternative delivery systems for THC and derivatives, (Cannabinoids), PCT filing submitted April, 2003.
M. A. Repka, Delivery of medicaments to the nail and perionychium, Patent submitted April 2004.
AWARDS AND HONORS
Mr. Srinivasa Murthy Sammeta (Pharmaceutics Graduate Student) received a Graduate Student Council Research Grant for 2007-08 funded by the Graduate Student Council of the University of Mississippi for his project entitled, “Needle Free Method of Measuring Blood Glucose”.
Mr. Sridhar Thumma (Pharmaceutics Graduate Student) was presented with an outstanding podium presentation award for his podium entitled, “Transmucosal Delivery of a Pro-drug of Delta-9-Tetrahydrocannabinol” at the Pharmforum 2007 conference, hosted by the University of Tennessee Student Chapter of the American Association of Pharmaceutical Scientists (AAPS) in May 2007.
Mr. Sridhar Thumma received the Natural Products Neuroscience (CORE-NPN) Fellowship funded by the National Institute of Health for the year 2006-07.
Ms. Sampada Upadhye (Pharmaceutics Graduate Student) was presented with the Best Poster Award in Health Sciences II category for her poster entitled, “Wound Healing Potential of Chlorophyllin Gel” at the University of Mississippi Sigma Xi Poster Symposium in March 2007.
Ms. Upadhye also won the outstanding poster award during the AAPS Pharmforum 2007 conference, TN.
Ms. Sampada Upadhye, Mr. Srinivasa Murthy Sammeta and Mr. Ramesh Srirangam received the Natural Products Neuroscience (CORE-NPN) Fellowship funded by the National Institutes of Health for 2007-08
Mr. Siva Ram Kiran Vaka (Pharmaceutics Graduate Student) received a UM Graduate Student Council Research Grant for 2007-08 for his project entitled, “Enhancement of Brain Uptake of Intranasally Administered Macromolecular Therapeutics”.
Ms. Sampada Upadhye has been selected for inclusion in The University of Mississippi’s 2007-2008 class for “Who’s Who Among Students in American Universities and Colleges”.
Mr. Sridhar Thumma received outstanding presenter award at 2006 Sigma-Xi Annual poster presentation
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